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Without adequate B12, these processes become impaired, leading to potentially serious health consequences

Funding Australian Research Council Industrial Transformation Training Centre for Personalised Therapeutics Technologies (IC170100016), Western Australia Innovation Seed Fund (2022/GR000685), the Program of Science and Technology of Guangzhou (202102020427), and Guang Dong Basic and Applied Basic Research Foundation (2021A1515011008

Tirzepatide is composed of 39 amino acids, is amidated at the C-terminal, conjugates a C20 fatty diacid moiety via a spacer connected to Lys 20 , and has a half-life of 116.7 h

Levels of the hormone rise slowly, then spike to signal fullness