Liu F, Horton-Sparks K, Hull V, Li RW, Martinez-Cerdeno V
The impact on the vagus nerve becomes clear: Dysregulated stress response feeling stuck in fight-or-flight, even at rest Disrupted appetite signaling constant hunger with little sense of satiety Sluggish digestion delayed gastric emptying and toxin buildup This combination often leads to increased cravings, stress eating, and weight gainnot because of a lack of willpower, but because the system itself is out of balance
Short-acting GLP-1RAs exhibit a considerable fluctuation in circulating levels during the daytime that, in turn, produce an intermittent activation of GLP-1R, resulting in different pharmacodynamic effects compared to long-acting GLP-1RA (66)
confirming effectiveness, monitoring side effects, and comparing the new treatment to standard of care