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WADA only prohibits a few specific peptides that are, or have the potential to be, performance enhancing (listed above)

They are more prone to developing new allergies, including contact allergies to topical agents

Shared Risk Factors Aging and reduced absorption capacity Sedentary indoor lifestyle Limited sun Vegetarian or restrictive diets Gastrointestinal disorders (gastritis, IBS, celiac disease) Long-term use of proton pump inhibitors or metformin And when both are low, the effects compound

Researchers raise doses in animals until roughly 50% die, giving a crude measure of acute lethality that does not translate directly to human safety but gives context for risk margins