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Cross-sectional clinical study Group comparisons of brain outcome measures were conducted using linear regression analysis, with the healthy control group serving as the reference category

LRRK2 and PINK1 form a functional protein kinase pair to modulate TH and DA levels in dopaminergic neurons, and this observation has been validated in multiple in vitro and in vivo PD models, including human dopaminergic neurons and midbrain organoid models derived from patient cell-induced iPSCs [44]

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Pratter of the US District Court for the Eastern District of Pennsylvania previously appointed attorneys form Levin Papantonio Rafferty Proctor Buchanan OBrien Barr & Mougey PA, Pogust Goodhead, and Johnson Becker PLLC, among others, to the plaintiffs committee