foxo4-dri senolytic peptide study Molecular modelling of the FOXO4-TP53 interaction to design peptides for the elimination of senescent cancer cells Targeted Apoptosis of Senescent Cells

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Nowadays, FOXO4-DRI studies are focused on the following aspects: osteoarthritis (senescent chondrocyte clearance), metabolic dysfunction (insulin resistance and obesity-associated senescence), neurodegeneration (eliminating senescent brain cells), and fibrotic diseases (idiopathic pulmonary and liver fibrosis)