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Specifically, liraglutide downregulated expression of Haptoglobin (Hp), upregulated levels of PRKC apoptosis WT1 regulator (PAWR), and synapse-related proteins including Syn1, Pde2a, Dpysl2, Nf1, Bsn, and Map1b, and increased the densities of neurons and synapses

Instead, low glutathione in the rest of the body could be due to an increased use of it for combating oxidative stress.[ref] Neurodegenerative diseases: Alzheimers, Parkinsons, and MS are all characterized by neuronal injury from oxidative stress

Now picture a gentler path: slower weight change, protein-rich meals, an evening wind-down routine, and structured check-ins with a clinician