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Cannabis and GLP-1 medications can send different signals about hunger and pleasure, and people experience that interaction differently

This relatively long half-life has led some to theorise that extended dosing might maintain adequate blood levels

Since unilateral T-RDN and bilateral A-RDN had comparable effects on GLP-1 mediated hemodynamic changes, it is possible that unilateral interruption of renal afferent input (limited input) to the central nervous system is sufficient to reduce sympathetic outflow affecting GLP-1 mediated hemodynamic changes

Mounjaro acts on both GLP-1 and GIP receptors, while Wegovy contains semaglutide, which works on the GLP-1 pathway only