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Clinical Biochemistry, 48 (16-17), 1200-1208

[1] Without early administration of the antidote, fulminant liver failure follows, often in combination with kidney failure, and death generally occurs within several days

Within the tumor microenvironment (TME), tumor cells reprogram glucose, lipid, and amino acid metabolism to competitively deplete critical nutrients (e.g., glucose, glutamine, arginine) and accumulate inhibitory metabolites (e.g., lactate), thereby suppressing CD8 + T cell function and proliferation to facilitate immune evasion (Tharp et al., 2024

IV therapy effects and duration vary by individual and treatment type.