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The underlying mechanisms were investigated, leading to the discovery that in strains expressing high levels of gdhA mRNA, two promoters, gdhA P1 and gdhA P2, initiate transcription of gdhA

The most commonly reported side effects are gastrointestinal in naturenausea, vomiting, or diarrhoeaparticularly when starting oral supplementation

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DOI: 10.1016/j.bbadis.2011.10.003