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The combination of chemotherapeutic drugs and ferroptosis inducers can reverse drug resistance in HER2+ breast cancer [86]

In addition to paracrine signaling, CAFs can directly supply iron to PDAC cells [57]

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Antioxidant Signaling and ROS Attenuation Studies in aged rodent models demonstrated that Epitalon treatment reduced markers of oxidative stress, including lipid peroxidation products (MDA) and protein carbonylation, while upregulating superoxide dismutase (SOD) and catalase activity