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Back in 2024, research presented at the European Congress on Obesity found that people who gradually reduced their GLP-1s dose to zero over the course of nine weeks were able to maintain a stable body weight in the first 26 weeks post-GLP-1s

GLP-1 also suppresses secretion of glucagon from cell of pancreas and concentration of glucose in blood after meal

Fourth, achieving selective drug delivery to tumor cells without affectingnormal cells is technically difficult, requiring sophisticated carriers or prodrugs