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2024, doi: 10.1016/j.annemergmed.2024.03.007

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation

Signs of a severe allergic reaction (anaphylaxis) include: Skin rash, hives, or severe itching Swelling of the face, lips, tongue, or throat Difficulty breathing or wheezing A rapid heartbeat or a sudden drop in blood pressure If you ever develop swelling of the face or throat, trouble breathing, or other signs of a severe reaction after any injection, treat it as an emergency and call 911