glp-1 dosing Injections of an ultra-long-acting investigational agonist led to significant weight loss in people with overweight or obesity, with reductions continuing after a switch to once-monthly dosing, according to the ongoing VESPER From weekly to quarterly dosing:

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Two mortalities were recorded in the highest (5000 mg/kg) and medium (2900 mg/kg) dose groups after 24 hours, but none were recorded in the lowest (1600 mg/kg) dose group

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