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However, the VA National Criteria for Use guidelines for checkpoint inhibitor initiation explicitly allow use only for ECOG performance status score of 0 or 1 for all immunotherapy agents, with some exceptions for ECOG performance status score of 0 to 2 for nivolumab and pembrolizumab

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S2CID 24375953

El International Citicoline Trial on acUte Stroke (ICTUS) es un estudio multicntrico y doble ciego que evalu el efecto de suplementar a 2,298 pacientes con accidente cerebrovascular isqumico agudo con citicolina (2,000 mg/da) o un placebo durante seis semanas sobre varios resultados funcionales y neurolgicos y en la tasa de mortalidad (94)