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The responses to formalin-induced pain, such as licking and biting of the injected paw, are biphasic

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The main lipid peroxidation products are hydroperoxides, such as propanal, hexanal, 4-hydroxynonenal, and malondialdehyde (MDA) (37)

The Demopoulos patent also references as the preferred embodiment of the invention the combination of glutathione and ascorbic acid which is needed to maintain the reduced state of the glutathione and to facilitate its function