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Though we highlight the space as a promising area of focus for the future of healthcare, immense challenges remain before these drugs are effectively (and widely) integrated into routine clinical care

ZeissigSBrgelNGnzelDRichterJMankertzJWahnschaffeUet alChanges in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohns disease