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49 Elevated inflammatory factors in T2D such as IL-6 and interferon- (IFN-) cand bind to their receptors, activate JAK2/STAT3, subsequently upregulates the expression of suppressor of cytokine signaling 3 (SOCS3), which inhibit IRS-1 cascade

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The figure below shows the absorption, metabolism, and excretion of vitamin E

Nature 375:599603 Farber K, Kettenmann H (2005) Physiology of microglial cells