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doi: 10.1016/j.biortech.2010.02.111 212 WuS.ZhaoX.ShenH.WangQ.ZhaoZ

Six new polyoxygenated xanthones from garcinia cowa and their neuroprotective effects on glutamatemediated hippocampal neuronal HT22 cell death

It explores the mechanisms, advantages, and challenges of established methods such as TMS and tDCS, as well as emerging approaches such as magnetothermal stimulation and FUS, highlighting a promising alternative for targeted neuromodulation

Split dosing may help if: single morning dose produces effects that fade by afternoon, you are using higher doses (450-500mcg) where sustained levels may help, or evening administration fits your schedule better than early morning