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Local injection site reactions are the most common and typically include: Erythema (redness) and warmth at the injection site Swelling or induration (hardening of tissue) Pruritus (itching) or discomfort Bruising or nodule formation in some cases (particularly with exenatide extended-release formulations, where nodules are common and often non-allergic) These reactions usually appear within hours of injection and may resolve spontaneously within a few days

Tesofensine, conversely, works in the brain as a triple monoamine reuptake inhibitor, affecting serotonin, norepinephrine, and dopamine to suppress appetite

Inflammatory cells Neutrophil Neutrophil is an important part of the cellular response to inflammation, which migrates to the inflammatory site and directly engulfs pathogens to kill bacteria

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