Intensity and distribution of brain lesions (red neurons) (swollen or ballooned neurons are a future of the axon reaction and a variety of disease in which perikaryal changes occur independently of axonal damage
However, current evidence suggests that the disorder arises from a complex interplay of genetic predisposition, altered monoamine neurotransmission, and structural brain abnormalities, which together increase susceptibility
But with age, like many other functions, this antioxidant production can slow down and leave cells more susceptible to harmful free radicals
Subbiah V, Khawaja MR, Hong DS, Amini B, Yungfang J, Liu H, Johnson A, Schrock AB, Ali SM, Sun JX, Fabrizio D, Piha-Paul S, Fu S, Tsimberidou AM, Naing A, Janku F, Karp DD, Overman M, Eng C, Kopetz S , Meric-Bernstam F, Falchook GS