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Nonetheless, the exact mechanisms underlying the GLP-1 RA-associated HR acceleration are still unclear and these preliminary study results involving healthy male subjects cannot be over-generalized to a diabetic population using GLP-1 RAs

The medication is studied in a specific protocol, with doses increased step by step, not passed around as a shortcut

Baseline laboratory investigations are recommended to assess liver function, kidney function, oxidative stress markers, and nutritional deficiencies prior to initiating therapy

This gradual increase helps the body adapt to the medication and improves weight loss outcomes