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Many have reported a positive inotropic effect, with exogenous LCAC concentrations as low as 110 M reported to increase guinea pig papillary muscle tension by 15100% dose-dependently (Nakaya and Tohse, 1986

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Research is currently underway to see if taking oral weight-loss medication (such as bupropion-naltrexone) can help ease the transition off GLP-1 receptor agonists and reduce the amount of weight that's typically regained after stopping them

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doi: 10.1210/clinem/dgaa430, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 29

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