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GLP-1 medications mimic this hormone, effectively restoring the appetite and glucose regulation system that chronic overeating, insulin resistance, and metabolic dysfunction have disrupted
Using a nanoluciferase tag at the GLP-1R C-terminus, we were also able to obtain BRET measurements of GLP-1R redistribution to early, late and recycling endosomes that corroborate the TR-FRET responses
So is it giving like a timeout to the digestive system
Dive Insight: Wall Street analysts and even big pharmaceutical company CEOs like Pfizers Albert Bourla are making ambitious sales forecasts for GLP-1 drugs, predicting annual global sales could reach as high $90 billion by the end of the decade
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