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The vitamin K pathway Vitamin E is considered as the most potent lipophilic antioxidant that traps free radicals

TLR1/2/6 activation and subsequent signal transduction may be in part responsible for clinical immunopathological manifestations found in patients infected with COVID-19 (Gadanec et al., 2021)

Two trials in acutely hospitalized patients have shown that short-term (around 7 days) vitamin C supplementation increased concentrations of ascorbic acid in plasma and leukocytes and led to 34-35% improvements in mood state, as measured by POMS (142, 143)

It is synthesised primarily in the liver and is the most abundant endogenous (body-produced) antioxidant in human cells, with concentrations highest in hepatic, lung, kidney, and immune tissue