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Abstract Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors are commonly used treatments for patients with type 2 diabetes mellitus (T2DM)

August 26, 2006

It appears to reverse cardiac damage by increasing blood vessel growth in injured tissues and activating a cardiac response that may promote healing of the cardiac tissue after an event of myocardial infarction

These mechanisms influence cellular processes such as cell proliferation, differentiation, and metabolism, among others ( Intracellular receptors involved in the neuroactive steroids signal transduction are progesterone (PR, isoforms: PR-A, and PR-B), glucocorticoid (GR, with several splice variant isoforms, such as GR-), androgen (AR, with different splice variant), estrogen (ER, subtypes coded in different genes: ER, and ER), and mineralocorticoid receptor (MR, with several splice variant isoforms, including MR and MR)