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10,12,53,56 Overall, respiratory and cardiac diseases account for 38% and 16% of deaths in these patients, respectively
Daugas E, Cand C, Kroemer G
Commonly reported side effects in trials include: Gastrointestinal effects: nausea, vomiting, diarrhoea, constipation, and abdominal discomfort these are most prevalent during dose escalation and typically diminish over time
These include: Dulaglutide (Trulicity) : Once-weekly injection with a single-dose pen featuring an automatic injection mechanism Semaglutide (Ozempic) : Once-weekly administration with dose escalation from 0.25 mg to maintenance doses of 0.5 mg, 1 mg, or 2 mg Exenatide extended-release (Bydureon BCise) : Once-weekly microsphere suspension requiring resuspension before injection Liraglutide (Victoza) : Once-daily injection available in a multi-dose pen For weight management, semaglutide 2.4 mg (Wegovy) and liraglutide 3.0 mg (Saxenda) are specifically FDA-approved
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