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Risk varies by formulation (e.g., NPH and premixed have higher risk than basal analogs) Drugs that increase insulin secretion Other medications (evidence for many of these drugs is questionable) +/- Renal failure * Other diabetes medications not listed above (these usually dont cause hypoglycemia on their own, but may synergize with other risk factors)

Within the central nervous system, glutamate (Glu) functions as the primary excitatory neurotransmitter released from presynaptic terminals

These assessments are as follows: above average (more than 109), average (90109), low average (8089), low (7079), and very low (less than 70)