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Therefore, to eliminate the potential baseline effect of different studies, the rates of body weight change from the initial values were selected as the therapeutic index, which was a better indicator used to assess changes in body weight

10.1038/nrm3735 146 MatsudaF.InoueN.GotoY.MaedaA.ChengY.SakamakiK.et al (2008)

Studies have indicated that Zn-induced overexpression of MT in pancreatic -cells can confer notable protection against streptozotocin-induced diabetes in both rats and mice [125]