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To investigate the molecular mechanism of GDH, we determined a crystal structure of the Corynebacterium glutamicum-derived GDH (CgGDH) in complex with its NADP cofactor and -ketoglutarate substrate

Older adults are more susceptible to obesity- and type 2 diabetesrelated metabolic dysfunctions like glucose intolerance, insulin resistance, hepatic steatosis, and inflammation in adipose tissues upon high calorie/fat intake (3437)

He urged lawmakers to consider changes, including: Requiring transparent net pricing that would be reported to the state

The variants did not appear to influence responses to other commonly prescribed diabetes medications such as metformin, sulfonylureas or DPP-4 inhibitors