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Saliva samples were taken at short intervals (every 15 to 20 min) between 9:50 and 12:00 pm

Important research boundary: These clinical trial results were achieved with FDA-approved branded medications studied under controlled conditions with specific manufacturing processes, quality controls, and dosing protocols

doi: 10.1016/s0736-4679(01)00438-3 [PubMed] 20049080 Bolder U, Ebener C, Hauner H, Jauch KW, Kreymann G, Ockenga J, Traeger K

The novel BH3 alpha-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak