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For example, the SPARC level increased in the skeletal muscles of young male subjects after 11 weeks of a strength-training program [21], and it transiently increased in the serum of young healthy men immediately after a single bout of cycling [22]

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4.1 The role of GLP-1 RAs in IBD The previously mentioned intrinsic connection between metabolism and the inflammatory response led researchers to investigate the role of GLP-1 modulation in the management of IBD