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The medication was only approved in 2022 and 2023, making it too new for meaningful pregnancy outcome data to have accumulated

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Hyperphagia in BBS appears to result from multifactorial disruptions, whereby intrinsic defects in CCK signaling pathways and receptor function further exaggerated obesity-related resistance to satiety signals (31)

Neuroprotection research includes hippocampal ischemia-reperfusion models in rats (PMID 32558293) and investigations into the brain-gut axis as a candidate explanatory framework for the broad effects observed across tissue types (PMID 27138887)