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Having met the MHRAs rigorous standards of safety, quality and effectiveness, the semaglutide tablet has been approved in the UK for weight loss and weight management, says Julian Beach, executive director of healthcare quality and access at the Medicines and Healthcare Regulatory Authority

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Main outcome measures Cox proportional hazards models were fitted to estimate the hazard ratios and 95% confidence intervals of major adverse cardiovascular events and serious renal events, separately, comparing the GLP-1 receptor agonist-SGLT-2 inhibitor combination with the background drug, either GLP-1 receptor agonists or SGLT-2 inhibitors, depending on the cohort

10.1111/j.1748-1716.2007.01713.x 51 LaursenP