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However, it has become clear that the most widely used enzyme-linked immunosorbent assays (ELISA) do not detect zonulin but complement C3 and possibly properdin, a related molecule from the same family with unclear functional effects (73, 74)

Nuclear factor erythroid 2-related factor (Nrf2) is also a regulator of oxidative stress, involved through the transcription of antioxidant detoxification genes (206)

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