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Neurology 68 , 18311836 (2007)
Karuppagounder SS, Alin L, Chen Y, Brand D, Bourassa MW, Dietrich K, Wilkinson CM, Nadeau CA, Kumar A, Perry S, Pinto JT, Darley-Usmar V, Sanchez S, Milne GL, Pratico D, Holman TR, Carmichael ST, Coppola G, Colbourne F, Ratan RR (2018) N-acetylcysteine targets 5 lipoxygenase-derived, toxic lipids and can synergize with prostaglandin E(2) to inhibit ferroptosis and improve outcomes following hemorrhagic stroke in mice
The detected cellular iron was in the range of 28 10 g/g of cells for 48-h incubation with 100 M Fe-NTA, whereas control cells contained 7.2 1.9 g iron/g of cells (Fig
Plasma glycerol changes were also blunted
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