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The other hierarchic aspect is connected with the patterns of expression of certain potentially more essential selenoproteins (Novoselov et al., 2005) in certain tissues, first of all in the brain, to maintain these important selenoproteins at a high level even at Se deficiency

Efforts to reduce lipid levels can even promote disease progression, as FAO may induce oxidative stress, exhausting antioxidant competences and promoting damage to cellular organelles and DNA

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H2S promotes DNA methylation and protein production for cancer growth, creating oxidative stress that activates platelets and white blood cells