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SKU: 16998186255
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SKU: 16998186255

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Description

cGAS/STING pathway in microglial diseases In the context of neurodegeneration, amplification of microglial cGAS-STING signaling, along with IFN production and cGAS-driven senescence, has been implicated as a disease-promoting mechanism in female mice ( R47H variant, indicating both associated with increased risk and earlier onset of Alzheimer's disease and their potential role as upstream modulators of AD pathogenesis (Yu et al., 2020)