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Some animals in the ML162 treated group were excluded from the toe spreading assay because they developed a toe-biting phenotype, which is known to associate with sciatic nerve surgery in rodents 108

doi: 10.1002/bjs.4786 84 OrabuezeIMasucciACluzetV

Since tesofensine has an effect on dopamine, let's first take a look at why that matters by talking about dopamine adaptation

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