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Semaglutide 2.4 mg cut mean body weight about 14.9 percent at 68 weeks (STEP 1), tirzepatide 15 mg about 20.9 percent at 72 weeks (SURMOUNT-1), and in the only head-to-head, tirzepatide beat semaglutide 20.2 percent versus 13.7 percent at 72 weeks (SURMOUNT-5, n=751)