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Dinkele, R

As we age, mitochondrial function can decline, leading to reduced energy production and a metabolic slowdown

Animal studies demonstrate that dihydrotestosterone (DHT) treatment upregulates ferroptosis-related markers ( e.g ., ACSL4) in ovarian cells, suggesting that androgens may exacerbate ferroptosis by modulating lipid metabolism genes ( 3.4 Epigenetic modifications Growing evidence has elucidated the critical role of epigenetic modifications in the pathogenesis and progression of PCOS