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100 The platelet endothelial cell adhesion molecule (PECAM-1)/CD31, which provides sites for the attachment of monocytes and neutrophils, highly enriched at cell-cell junctions, participates in the process of inflammation, trauma healing 101 and the entry of a number of viruses into the platelet (e.g., human defective virus, poliovirus)

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Its one of the more researched herbal ingredients for PMS and menstrual irregularity, and is commonly used to support progesterone balance, which can directly affect mood swings and cycle-related symptoms