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CD8 + T cells were activated and treated with ML226 for 11 days, as previously described, incubated at 21%, 5% or 1% oxygen for 2 h, and then reactivated with anti-CD3/CD28 Dynabeads

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While some localized reactions occurred, no severe adverse events were reported, underscoring that SLIT could be a safe and effective desensitization approach for shrimp allergy in select patients [109]