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Citation15 The GSH/GSSG ratio serves as a key indicator of cellular redox status and may influence bacterial tolerance to antibiotics by regulating oxidative stress responses and protein thiol homeostasis

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This allowed him to develop a broad classification of proteins based on their extraction in a series of solvents ( However, the final fraction (glutelin) is more difficult to define, as it effectively comprises all proteins which are insoluble in the three previous solvents but can be solubilized under conditions of extreme pH