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Spreading redness extending beyond 2 inches from injection site Increasing pain or swelling after 48 hours Warmth, pus, or drainage from the site Fever over 100.4 degrees Fahrenheit Red streaks extending from the injection site Severe allergic symptoms: difficulty breathing, facial swelling, hives covering large body areas Lump that persists beyond 2 weeks or continues growing Allergic reactions range from mild and local to severe and systemic

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