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Ozempic (semaglutide 0.5 mg2 mg) is licensed for the treatment of type 2 diabetes only and is not approved for weight management

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The most extensively studied mechanism involves allosteric modulation of the GABAergic system, though research has also documented effects on monoamine neurotransmitter metabolism, enkephalin degradation pathways, and neurotrophic factor expression all of which may contribute synergistically to the behavioral effects observed in preclinical models