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For instance, studies on quercetins use in type 2 diabetes and cardiovascular diseases suggest efficacy in reducing oxidative stress and inflammatory markers ( To enhance treatment outcomes, combination therapies that pair quercetin with agents like NAC or corticosteroids may effectively address both oxidative stress and inflammation, improving therapeutic efficacy while minimizing adverse effects ( 4 Future directions Quercetin holds significant promise as a multi-target therapeutic in AP, thanks to its antioxidant, anti-inflammatory, and immune-modulatory properties (Sun et al., 2025)

Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain

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Gillette Guyonnet S, Andrieu S, Vellas B