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Physiologic replacement of both these incretin agents in the form of dual GLP-1/GIP receptor activating compounds (twincretins) has yielded encouraging results vis--vis glucose and body weight regulation

At the end of a seemingly ubiquitous commercial for telehealth company Ro, a characteristically flabbergasted Charles Barkley speaks for us all when he remarks, Wait, youre telling me they have a GLP-1 pill for weight loss now? They do and it turns out to be as wildly popular as its injectable predecessors

Of these, 652,001 patients with T2D and 573,443 with obesity were included in PSM

As kidney function declines, there is a decline in the ability of the kidney to increase potassium urine excretion after meals, eventually leading to chronic hyperkalemia