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CagriSema was generally well-tolerated, with mild to moderate gastrointestinal adverse events, primarily nausea and vomiting [124]

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The result is a sustained elevation of GH and IGF-1 over several days from a single dose, dosed roughly once or twice weekly

Reda A, Veys K, Kadam P, Taranta A, Rega LR, Goffredo BM, Camps C, Besouw M, Cyr D, Albersen M, Spiessens C, de Wever L, Hamer R, Janssen MCH, DHauwers K, Wetzels A, Monnens L, van den Heuvel L, Goossens E, Levtchenko E (2021) Human and animal fertility studies in cystinosis reveal signs of obstructive azoospermia, an altered blood-testis barrier and a subtherapeutic effect of cysteamine in testis