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the physiological impact is less central than MC3/MC4 but can contribute to overall systemic effects 4

Adults who had given consent performed a 12-hour fast overnight before performing the l-carnitine challenge test, which involved a baseline blood sample and then oral consumption ( t 0 at time of initial ingestion) of capsules containing 250 mg d 3 -l-carnitine (under investigational new drug exemption)