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Therefore, therapeutic strategies targeting RAAS activation, such as MR antagonists, are vital for managing complications related to cirrhosis[55]

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In terms of the inhibitory effect of MG on selenoproteins and its impact on GSH metabolism, our study demonstrated that MG not only forms a complex with GSH but also significantly hinders the biosynthesis of selenoproteins, which serve as crucial components of antioxidant defence mechanisms and play active roles in the glutathione peroxidase GPX4

M., Roux, J., Bariohay, B., Rouquet, T., & Baar, K